Cargando…

WHO should accelerate, not stall, rectal artesunate deployment for pre-referral treatment of severe malaria

The recent World Health Organization moratorium on rectal artesunate (RAS) for pre-referral treatment of severe childhood malaria is costing young lives. The decision was based on disappointing findings from a large observational study that provided RAS to community health workers with little traini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peto, Thomas J, Watson, James A, White, Nicholas J, Dondorp, Arjen M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318884/ https://www.ncbi.nlm.nih.gov/pubmed/36722432 http://dx.doi.org/10.1093/trstmh/trad002

Ejemplares similares

Rectal artesunate suppositories for the pre-referral treatment of suspected severe malaria
por: Watson, James A., et al.
Publicado: (2023)

Pre‐referral rectal artesunate for severe malaria
por: Okebe, Joseph, et al.
Publicado: (2014)

Stopping prereferral rectal artesunate — a grave error
por: Watson, James A, et al.
Publicado: (2022)

Pre-referral rectal artesunate in severe malaria: flawed trial
por: Hirji, Karim F, et al.
Publicado: (2011)

Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial
por: Gomes, MF, et al.
Publicado: (2009)

Response to: Pre-referral rectal artesunate in severe malaria: a flawed trial
por: Gomes, Melba F
Publicado: (2011)

The CARAMAL study could not assess the effectiveness of rectal artesunate in treating suspected severe malaria
por: Watson, James A., et al.
Publicado: (2023)

Recognition, Perceptions and Treatment Practices for Severe Malaria in Rural Tanzania: Implications for Accessing Rectal Artesunate as a Pre-Referral
por: Warsame, Marian, et al.
Publicado: (2007)

Artesunate Dosing in Severe Falciparum Malaria
por: Dondorp, Arjen M., et al.
Publicado: (2012)

Pre-referral rectal artesunate is no “magic bullet” in weak health systems
por: Hetzel, Manuel W., et al.
Publicado: (2023)

An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria
por: Saralamba, Sompob, et al.
Publicado: (2023)

Understanding caretakers' dilemma in deciding whether or not to adhere with referral advice after pre-referral treatment with rectal artesunate
por: Simba, Daudi O, et al.
Publicado: (2010)

Population Pharmacokinetics of Artesunate and Dihydroartemisinin following Intra-Rectal Dosing of Artesunate in Malaria Patients
por: Simpson, Julie A, et al.
Publicado: (2006)

Adherence to the referral advice after introduction of rectal artesunate for pre-referral treatment of severe malaria at the community level: a noninferiority trial in the Democratic Republic of the Congo
por: Mvumbi, Patrick M., et al.
Publicado: (2019)

Counterfeit artesunate antimalarials in southeast Asia
por: Newton, Paul N, et al.
Publicado: (2003)

Pre-referral intranasal artesunate powder for cerebral malaria: a proof-of-concept study
por: Kouakou, Yobouet Ines, et al.
Publicado: (2022)

Deployment of Early Diagnosis and Mefloquine- Artesunate Treatment of Falciparum Malaria in Thailand: The Tak Malaria Initiative
por: Carrara, Verena Ilona, et al.
Publicado: (2006)

Pharmacokinetic Study of Rectal Artesunate in Children with Severe Malaria in Africa
por: Fanello, Caterina, et al.
Publicado: (2021)

Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study
por: Hetzel, Manuel W., et al.
Publicado: (2022)

Rectal artesunate for severe malaria, implementation research, Zambia
por: Green, Cathy, et al.
Publicado: (2023)

Acceptability of pre-referral rectal artesunate for severe malaria in children under 5 years by health workers and caregivers in the Democratic Republic of the Congo, Nigeria and Uganda
por: Awor, Phyllis, et al.
Publicado: (2022)

Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria and Uganda
por: Brunner, Nina C, et al.
Publicado: (2022)

Use of rectal artesunate for severe malaria at the community level, Zambia
por: Green, Cathy, et al.
Publicado: (2019)

Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: An operational study
por: Signorell, Aita, et al.
Publicado: (2023)

Does Artesunate Prolong the Electrocardiograph QT Interval in Patients with Severe Malaria?
por: Maude, Richard J., et al.
Publicado: (2009)

Correction: Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: An operational study
por: Signorell, Aita, et al.
Publicado: (2023)

A Randomized Comparison of Dihydroartemisinin-Piperaquine and Artesunate-Amodiaquine Combined With Primaquine for Radical Treatment of Vivax Malaria in Sumatera, Indonesia
por: Pasaribu, Ayodhia Pitaloka, et al.
Publicado: (2013)

Community understanding of the concept of pre-referral treatment and how this impacts on referral related decision-making following the provision of rectal artesunate: a qualitative study in western Uganda
por: Strachan, C. E., et al.
Publicado: (2018)

Feasibility, acceptability and impact of integrating malaria rapid diagnostic tests and pre-referral rectal artesunate into the integrated community case management programme. A pilot study in Mchinji district, Malawi
por: Phiri, Themba B., et al.
Publicado: (2016)

Severe falciparum malaria treated with artesunate complicated by delayed onset haemolysis and acute kidney injury
por: Plewes, Katherine, et al.
Publicado: (2015)

Clinical trials of artesunate plus sulfadoxine-pyrimethamine for Plasmodium falciparum malaria in Afghanistan: maintained efficacy a decade after introduction
por: Awab, Ghulam Rahim, et al.
Publicado: (2016)

Preparations of Rectal Suppositories Containing Artesunate
por: Persaud, Suzanne, et al.
Publicado: (2020)

Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia
por: Kefyalew, Takele, et al.
Publicado: (2016)

Effect of High-Dose or Split-Dose Artesunate on Parasite Clearance in Artemisinin-Resistant Falciparum Malaria
por: Das, Debashish, et al.
Publicado: (2013)

Pre-referral Rectal Artesunate Treatment by Community-Based Treatment Providers in Ghana, Guinea-Bissau, Tanzania, and Uganda (Study 18): A Cluster-Randomized Trial
por: Warsame, Marian, et al.
Publicado: (2016)

Compliance With Referral Advice After Treatment With Prereferral Rectal Artesunate: A Study in 3 Sub-Saharan African Countries
por: Siribié, Mohamadou, et al.
Publicado: (2016)

Are national treatment guidelines for falciparum malaria in line with WHO recommendations and is antimalarial resistance taken into consideration? – A review of guidelines in non‐endemic countries
por: Visser, Marc T., et al.
Publicado: (2022)

Should India be considering deployment of the first malaria vaccine RTS, S/AS01?
por: Rahi, Manju, et al.
Publicado: (2022)

Deploying triple artemisinin-based combination therapy (TACT) for malaria treatment in Africa: ethical and practical considerations
por: Tindana, Paulina, et al.
Publicado: (2021)

The message on malaria is clear: progress has stalled
por: Noor, Abdisalan M, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_slk7nnlhggh6fbm6b495sdtqe7