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Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19

OBJECTIVES: To prospectively assess health-related quality of life (HRQoL), global functionality, and disability in primary caregivers of surviving children and adolescents after COVID-19. METHODS: A longitudinal observational study was carried out on primary caregivers of surviving pediatric post-C...

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Autores principales: Martins, Fernanda, Gonçalves, Fernanda T., Imamura, Marta, Barboza, Daniela S., Matheus, Denise, Pereira, Maria Fernanda B., Marques, Heloisa H. S., Correa-Silva, Simone, Montenegro, Marilia M., Fink, Thais T., Lindoso, Livia, Bain, Vera, Ferreira, Juliana C. O. A., Astley, Camilla, Matsuo, Olivia M., Suguita, Priscila, Trindade, Vitor, Paula, Camila S. Y., Litvinov, Nadia, Palmeira, Patricia, Gualano, Bruno, Delgado, Artur F., Carneiro-Sampaio, Magda, Forsait, Silvana, Odone-Filho, Vicente, Antonangelo, Leila, Battistella, Linamara R., Silva, Clovis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319046/
https://www.ncbi.nlm.nih.gov/pubmed/37408752
http://dx.doi.org/10.3389/fpubh.2023.1117854
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author Martins, Fernanda
Gonçalves, Fernanda T.
Imamura, Marta
Barboza, Daniela S.
Matheus, Denise
Pereira, Maria Fernanda B.
Marques, Heloisa H. S.
Correa-Silva, Simone
Montenegro, Marilia M.
Fink, Thais T.
Lindoso, Livia
Bain, Vera
Ferreira, Juliana C. O. A.
Astley, Camilla
Matsuo, Olivia M.
Suguita, Priscila
Trindade, Vitor
Paula, Camila S. Y.
Litvinov, Nadia
Palmeira, Patricia
Gualano, Bruno
Delgado, Artur F.
Carneiro-Sampaio, Magda
Forsait, Silvana
Odone-Filho, Vicente
Antonangelo, Leila
Battistella, Linamara R.
Silva, Clovis A.
author_facet Martins, Fernanda
Gonçalves, Fernanda T.
Imamura, Marta
Barboza, Daniela S.
Matheus, Denise
Pereira, Maria Fernanda B.
Marques, Heloisa H. S.
Correa-Silva, Simone
Montenegro, Marilia M.
Fink, Thais T.
Lindoso, Livia
Bain, Vera
Ferreira, Juliana C. O. A.
Astley, Camilla
Matsuo, Olivia M.
Suguita, Priscila
Trindade, Vitor
Paula, Camila S. Y.
Litvinov, Nadia
Palmeira, Patricia
Gualano, Bruno
Delgado, Artur F.
Carneiro-Sampaio, Magda
Forsait, Silvana
Odone-Filho, Vicente
Antonangelo, Leila
Battistella, Linamara R.
Silva, Clovis A.
author_sort Martins, Fernanda
collection PubMed
description OBJECTIVES: To prospectively assess health-related quality of life (HRQoL), global functionality, and disability in primary caregivers of surviving children and adolescents after COVID-19. METHODS: A longitudinal observational study was carried out on primary caregivers of surviving pediatric post-COVID-19 patients (n = 51) and subjects without COVID-19 (n = 60). EuroQol five-dimension five-level questionnaire (EQ-5D-5L) and 12-question WHO Disability Assessment Schedule 2.0 (WHODAS 2.0) were answered for both groups. The univariate regression analysis was carried out using SPSS (v 20) and significance was established at 5%. RESULTS: The median duration between COVID-19 diagnosis in children and adolescents and longitudinal follow-up visits was 4.4 months (0.8–10.7). The median age of children and adolescents caregivers with laboratory-confirmed COVID-19 was similar to primary caregivers of subjects without laboratory-confirmed COVID-19 [43.2 (31.6–60.9) vs. 41.5 (21.6–54.8) years, p = 0.08], as well as similar female sex (p = 1.00), level of schooling (p = 0.11), social assistance program (p = 0.28), family income/month U$ (p = 0.25) and the number of household’s members in the residence (p = 0.68). The frequency of slight to extreme problems (level ≥ 2) of the pain/discomfort domain according to EQ-5D-5L score was significantly higher in the former group [74% vs. 52.5%, p = 0.03, OR = 2.57 (1.14–5.96)]. The frequency of disability according to WHODAS 2.0 total score was similar to those without disability and unknown (p = 0.79); however, with a very high disability in both groups (72.5% and 78.3%). Further analysis of primary caregivers of children and adolescents with post-COVID-19 condition (PCC) [n = 12/51 (23%)] compared to those without PCC [n = 39/51(77%)] revealed no differences between demographic data, EQ-5D-5L and WHODAS 2.0 scores in both groups (p > 0.05). CONCLUSION: We longitudinally demonstrated that pain/discomfort were predominantly reported in approximately 75% of primary caregiver of COVID-19 patients, with high disability in approximately three-quarters of both caregiver groups. These data emphasized the prospective and systematic caregiver burden evaluation relevance of pediatric COVID-19.
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spelling pubmed-103190462023-07-05 Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19 Martins, Fernanda Gonçalves, Fernanda T. Imamura, Marta Barboza, Daniela S. Matheus, Denise Pereira, Maria Fernanda B. Marques, Heloisa H. S. Correa-Silva, Simone Montenegro, Marilia M. Fink, Thais T. Lindoso, Livia Bain, Vera Ferreira, Juliana C. O. A. Astley, Camilla Matsuo, Olivia M. Suguita, Priscila Trindade, Vitor Paula, Camila S. Y. Litvinov, Nadia Palmeira, Patricia Gualano, Bruno Delgado, Artur F. Carneiro-Sampaio, Magda Forsait, Silvana Odone-Filho, Vicente Antonangelo, Leila Battistella, Linamara R. Silva, Clovis A. Front Public Health Public Health OBJECTIVES: To prospectively assess health-related quality of life (HRQoL), global functionality, and disability in primary caregivers of surviving children and adolescents after COVID-19. METHODS: A longitudinal observational study was carried out on primary caregivers of surviving pediatric post-COVID-19 patients (n = 51) and subjects without COVID-19 (n = 60). EuroQol five-dimension five-level questionnaire (EQ-5D-5L) and 12-question WHO Disability Assessment Schedule 2.0 (WHODAS 2.0) were answered for both groups. The univariate regression analysis was carried out using SPSS (v 20) and significance was established at 5%. RESULTS: The median duration between COVID-19 diagnosis in children and adolescents and longitudinal follow-up visits was 4.4 months (0.8–10.7). The median age of children and adolescents caregivers with laboratory-confirmed COVID-19 was similar to primary caregivers of subjects without laboratory-confirmed COVID-19 [43.2 (31.6–60.9) vs. 41.5 (21.6–54.8) years, p = 0.08], as well as similar female sex (p = 1.00), level of schooling (p = 0.11), social assistance program (p = 0.28), family income/month U$ (p = 0.25) and the number of household’s members in the residence (p = 0.68). The frequency of slight to extreme problems (level ≥ 2) of the pain/discomfort domain according to EQ-5D-5L score was significantly higher in the former group [74% vs. 52.5%, p = 0.03, OR = 2.57 (1.14–5.96)]. The frequency of disability according to WHODAS 2.0 total score was similar to those without disability and unknown (p = 0.79); however, with a very high disability in both groups (72.5% and 78.3%). Further analysis of primary caregivers of children and adolescents with post-COVID-19 condition (PCC) [n = 12/51 (23%)] compared to those without PCC [n = 39/51(77%)] revealed no differences between demographic data, EQ-5D-5L and WHODAS 2.0 scores in both groups (p > 0.05). CONCLUSION: We longitudinally demonstrated that pain/discomfort were predominantly reported in approximately 75% of primary caregiver of COVID-19 patients, with high disability in approximately three-quarters of both caregiver groups. These data emphasized the prospective and systematic caregiver burden evaluation relevance of pediatric COVID-19. Frontiers Media S.A. 2023-06-20 /pmc/articles/PMC10319046/ /pubmed/37408752 http://dx.doi.org/10.3389/fpubh.2023.1117854 Text en Copyright © 2023 Martins, Gonçalves, Imamura, Barboza, Matheus, Pereira, Marques, Correa-Silva, Montenegro, Fink, Lindoso, Bain, Ferreira, Astley, Matsuo, Suguita, Trindade, Paula, Litvinov, Palmeira, Gualano, Delgado, Carneiro-Sampaio, Forsait, Odone-Filho, Antonangelo, Battistella and Silva. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Martins, Fernanda
Gonçalves, Fernanda T.
Imamura, Marta
Barboza, Daniela S.
Matheus, Denise
Pereira, Maria Fernanda B.
Marques, Heloisa H. S.
Correa-Silva, Simone
Montenegro, Marilia M.
Fink, Thais T.
Lindoso, Livia
Bain, Vera
Ferreira, Juliana C. O. A.
Astley, Camilla
Matsuo, Olivia M.
Suguita, Priscila
Trindade, Vitor
Paula, Camila S. Y.
Litvinov, Nadia
Palmeira, Patricia
Gualano, Bruno
Delgado, Artur F.
Carneiro-Sampaio, Magda
Forsait, Silvana
Odone-Filho, Vicente
Antonangelo, Leila
Battistella, Linamara R.
Silva, Clovis A.
Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19
title Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19
title_full Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19
title_fullStr Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19
title_full_unstemmed Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19
title_short Health-related quality of life and functionality in primary caregiver of surviving pediatric COVID-19
title_sort health-related quality of life and functionality in primary caregiver of surviving pediatric covid-19
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319046/
https://www.ncbi.nlm.nih.gov/pubmed/37408752
http://dx.doi.org/10.3389/fpubh.2023.1117854
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