Combining immunotherapy with high-dose radiation therapy (HDRT) significantly inhibits tumor growth in a syngeneic mouse model of high-risk neuroblastoma

PURPOSE: The mortality in patients with MYCN-amplified high-risk neuroblastoma remains greater than 50% despite advances in multimodal therapy. Novel therapies are urgently needed that requires preclinical evaluation in appropriate mice models. Combinatorial treatment with high-dose radiotherapy (HD...

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Detalles Bibliográficos
Autores principales: Boboila, Shuobo, Okochi, Shunpei, Banerjee, Debarshi, Barton, Sunjay, Street, Cherease, Zenilman, Ariela L., Wang, Qi, Gartrell, Robyn D., Saenger, Yvonne M., Welch, David, Wu, Cheng-Chia, Kadenhe-Chiweshe, Angela, Yamashiro, Darrell J., Connolly, Eileen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319189/
https://www.ncbi.nlm.nih.gov/pubmed/37408891
http://dx.doi.org/10.1016/j.heliyon.2023.e17399

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