IGH rod-like tracer: An AlphaFold2 structural similarity extraction-based predictive biomarker for MRD monitoring in pre-B-ALL

Sequence variation resulting from the evolution of IGH clones and immunophenotypic drift makes it difficult to track abnormal B cells in children with precursor B cell acute lymphoblastic leukemia (pre-B-ALL) by flow cytometry, qPCR, or next-generation sequencing (NGS). The V-(D)-J regions of immuno...

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Detalles Bibliográficos
Autores principales: Zhuo, Zhongling, Wang, Qingchen, Li, Chang, Zhang, Lili, Zhang, Lanxin, You, Ran, Gong, Yan, Hua, Ying, Miao, Linzi, Bai, Jiefei, Zhang, Chunli, Feng, Ru, Chen, Meng, Su, Fei, Qu, Chenxue, Xiao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319212/
https://www.ncbi.nlm.nih.gov/pubmed/37408685
http://dx.doi.org/10.1016/j.isci.2023.107107

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