TRIAC disrupts cerebral thyroid hormone action via negative feedback and heterogenous distribution among organs

As 3,3′,5-triiodothyroacetic acid (TRIAC), a metabolite of thyroid hormones (THs), was previously detected in sewage effluent, we aimed to investigate exogenous TRIAC’s potential for endocrine disruption. We administered either TRIAC or 3,3′,5-triiodo-L-thyronine (LT3) to euthyroid mice and 6-propyl...

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Detalles Bibliográficos
Autores principales: Yamauchi, Ichiro, Hakata, Takuro, Ueda, Yohei, Sugawa, Taku, Omagari, Ryo, Teramoto, Yasuo, Nakayama, Shoji F., Nakajima, Daisuke, Kubo, Takuya, Inagaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319255/
https://www.ncbi.nlm.nih.gov/pubmed/37408688
http://dx.doi.org/10.1016/j.isci.2023.107135

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