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Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison

Although little information exists on the efficacy of deworming in wild ruminants, gastrointestinal nematodes have been found to demonstrate increasing drug resistance. The spread of drug-resistant strains may be increased by transmission among livestock and susceptible wildlife species, thus posing...

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Autores principales: Gałązka, Marta, Klich, Daniel, Filip-Hutsch, Katarzyna, Olech, Wanda, Anusz, Krzysztof, Pyziel, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319643/
https://www.ncbi.nlm.nih.gov/pubmed/37415923
http://dx.doi.org/10.1016/j.ijppaw.2023.06.005
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author Gałązka, Marta
Klich, Daniel
Filip-Hutsch, Katarzyna
Olech, Wanda
Anusz, Krzysztof
Pyziel, Anna M.
author_facet Gałązka, Marta
Klich, Daniel
Filip-Hutsch, Katarzyna
Olech, Wanda
Anusz, Krzysztof
Pyziel, Anna M.
author_sort Gałązka, Marta
collection PubMed
description Although little information exists on the efficacy of deworming in wild ruminants, gastrointestinal nematodes have been found to demonstrate increasing drug resistance. The spread of drug-resistant strains may be increased by transmission among livestock and susceptible wildlife species, thus posing a potential threat to endangered species, such as the European bison. The aim of the study was twofold: to identify the parasite loads in captive European bison with the use of coprological techniques, and to test the influence of other nearby ungulates on the richness of bison parasitofauna. Additionally, the efficacy of deworming procedures against gastrointestinal nematodes in bison was evaluated. The survey was based on a coprological investigation of 285 fecal samples from 156 European bison in 15 enclosures. The parasitofauna of the captive European bison was consistent with those of free-ranging populations. The highest prevalence was noted for Eimeria spp. oocysts (60.7%), strongyle eggs (50.9%), Fasciola hepatica eggs (13.1%), Dictyocaulus viviparus larvae (12.3%) and Trichuris sp. Eggs (9.47%). Moreover, the close proximity of other ungulate species resulted in a higher diversity of parasite species. In all cases, deworming with albendazole, fenbendazole and ivermectin proved to be ineffective against strongylids and Trichuris sp. The results of fecal egg count reduction test (FECRT) ranged from 37.2 to 99.6% (95% CI <90%) for albendazole; values >95% (95% CI = 41–100) were noted for fenbendazole, and FECRT ranged from 63.2 to 97.5 (95% CI = 0–99) for ivermectin. As the results of anthelmintic treatment are unsatisfactory, it seems justified to continue study in this area. Our study is the first large-scale attempt to evaluate the efficacy of anthelminthics in captive European bison. The potential sharing of parasite species between bison and other ungulates should also be further investigated from the perspective of minimizing the risk of the spread of drug-resistant parasite strains.
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spelling pubmed-103196432023-07-06 Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison Gałązka, Marta Klich, Daniel Filip-Hutsch, Katarzyna Olech, Wanda Anusz, Krzysztof Pyziel, Anna M. Int J Parasitol Parasites Wildl Article Although little information exists on the efficacy of deworming in wild ruminants, gastrointestinal nematodes have been found to demonstrate increasing drug resistance. The spread of drug-resistant strains may be increased by transmission among livestock and susceptible wildlife species, thus posing a potential threat to endangered species, such as the European bison. The aim of the study was twofold: to identify the parasite loads in captive European bison with the use of coprological techniques, and to test the influence of other nearby ungulates on the richness of bison parasitofauna. Additionally, the efficacy of deworming procedures against gastrointestinal nematodes in bison was evaluated. The survey was based on a coprological investigation of 285 fecal samples from 156 European bison in 15 enclosures. The parasitofauna of the captive European bison was consistent with those of free-ranging populations. The highest prevalence was noted for Eimeria spp. oocysts (60.7%), strongyle eggs (50.9%), Fasciola hepatica eggs (13.1%), Dictyocaulus viviparus larvae (12.3%) and Trichuris sp. Eggs (9.47%). Moreover, the close proximity of other ungulate species resulted in a higher diversity of parasite species. In all cases, deworming with albendazole, fenbendazole and ivermectin proved to be ineffective against strongylids and Trichuris sp. The results of fecal egg count reduction test (FECRT) ranged from 37.2 to 99.6% (95% CI <90%) for albendazole; values >95% (95% CI = 41–100) were noted for fenbendazole, and FECRT ranged from 63.2 to 97.5 (95% CI = 0–99) for ivermectin. As the results of anthelmintic treatment are unsatisfactory, it seems justified to continue study in this area. Our study is the first large-scale attempt to evaluate the efficacy of anthelminthics in captive European bison. The potential sharing of parasite species between bison and other ungulates should also be further investigated from the perspective of minimizing the risk of the spread of drug-resistant parasite strains. Elsevier 2023-06-19 /pmc/articles/PMC10319643/ /pubmed/37415923 http://dx.doi.org/10.1016/j.ijppaw.2023.06.005 Text en © 2023 The Authors. Published by Elsevier Ltd on behalf of Australian Society for Parasitology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Gałązka, Marta
Klich, Daniel
Filip-Hutsch, Katarzyna
Olech, Wanda
Anusz, Krzysztof
Pyziel, Anna M.
Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison
title Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison
title_full Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison
title_fullStr Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison
title_full_unstemmed Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison
title_short Endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive European bison
title_sort endoparasite loads and the efficacy of conventional anthelmintics against gastrointestinal nematodes in captive european bison
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319643/
https://www.ncbi.nlm.nih.gov/pubmed/37415923
http://dx.doi.org/10.1016/j.ijppaw.2023.06.005
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