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A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity

Mechanosensitive (MS) ion channels are a ubiquitous type of molecular force sensor sensing forces from the surrounding bilayer. The profound structural diversity in these channels suggests that the molecular mechanisms of force sensing follow unique structural blueprints. Here we determine the struc...

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Detalles Bibliográficos
Autores principales: Zhang, Mingfeng, Shan, Yuanyue, Cox, Charles D., Pei, Duanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319725/
https://www.ncbi.nlm.nih.gov/pubmed/37402734
http://dx.doi.org/10.1038/s41467-023-39688-8

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