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Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery

The adaptive mutation phenomenon has been drawing the attention of biologists for several decades in evolutionist community. In this study, we propose a quantum mechanical model of adaptive mutation based on the implications of the theory of open quantum systems. We survey a new framework that expla...

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Autores principales: Ghasemi, Fatemeh, Tirandaz, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319750/
https://www.ncbi.nlm.nih.gov/pubmed/37402822
http://dx.doi.org/10.1038/s41598-023-38019-7
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author Ghasemi, Fatemeh
Tirandaz, Arash
author_facet Ghasemi, Fatemeh
Tirandaz, Arash
author_sort Ghasemi, Fatemeh
collection PubMed
description The adaptive mutation phenomenon has been drawing the attention of biologists for several decades in evolutionist community. In this study, we propose a quantum mechanical model of adaptive mutation based on the implications of the theory of open quantum systems. We survey a new framework that explain how random point mutations can be stabilized and directed to be adapted with the stresses introduced by the environments according to the microscopic rules dictated by constraints of quantum mechanics. We consider a pair of entangled qubits consist of DNA and mRNA pair, each coupled to a distinct reservoir for analyzing the spreed of entanglement using time-dependent perturbation theory. The reservoirs are physical demonstrations of the cytoplasm and nucleoplasm and surrounding environments of mRNA and DNA, respectively. Our predictions confirm the role of the environmental-assisted quantum progression of adaptive mutations. Computing the concurrence as a measure that determines to what extent the bipartite DNA-mRNA can be correlated through entanglement, is given. Preventing the entanglement loss is crucial for controlling unfavorable point mutations under environmental influences. We explore which physical parameters may affect the preservation of entanglement between DNA and mRNA pair systems, despite the destructive role of interaction with the environments.
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spelling pubmed-103197502023-07-06 Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery Ghasemi, Fatemeh Tirandaz, Arash Sci Rep Article The adaptive mutation phenomenon has been drawing the attention of biologists for several decades in evolutionist community. In this study, we propose a quantum mechanical model of adaptive mutation based on the implications of the theory of open quantum systems. We survey a new framework that explain how random point mutations can be stabilized and directed to be adapted with the stresses introduced by the environments according to the microscopic rules dictated by constraints of quantum mechanics. We consider a pair of entangled qubits consist of DNA and mRNA pair, each coupled to a distinct reservoir for analyzing the spreed of entanglement using time-dependent perturbation theory. The reservoirs are physical demonstrations of the cytoplasm and nucleoplasm and surrounding environments of mRNA and DNA, respectively. Our predictions confirm the role of the environmental-assisted quantum progression of adaptive mutations. Computing the concurrence as a measure that determines to what extent the bipartite DNA-mRNA can be correlated through entanglement, is given. Preventing the entanglement loss is crucial for controlling unfavorable point mutations under environmental influences. We explore which physical parameters may affect the preservation of entanglement between DNA and mRNA pair systems, despite the destructive role of interaction with the environments. Nature Publishing Group UK 2023-07-04 /pmc/articles/PMC10319750/ /pubmed/37402822 http://dx.doi.org/10.1038/s41598-023-38019-7 Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ghasemi, Fatemeh
Tirandaz, Arash
Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery
title Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery
title_full Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery
title_fullStr Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery
title_full_unstemmed Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery
title_short Environment assisted quantum model for studying RNA-DNA-error correlation created due to the base tautomery
title_sort environment assisted quantum model for studying rna-dna-error correlation created due to the base tautomery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319750/
https://www.ncbi.nlm.nih.gov/pubmed/37402822
http://dx.doi.org/10.1038/s41598-023-38019-7
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