Cargando…

Antiviral activity of silver nanoparticles against the influenza A virus

Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Naumenko, Krystyna, Zahorodnia, Svitlana, Pop, Calin V., Rizun, Nodari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319835/
https://www.ncbi.nlm.nih.gov/pubmed/37416089
http://dx.doi.org/10.1016/j.jve.2023.100330
_version_ 1785068323335045120
author Naumenko, Krystyna
Zahorodnia, Svitlana
Pop, Calin V.
Rizun, Nodari
author_facet Naumenko, Krystyna
Zahorodnia, Svitlana
Pop, Calin V.
Rizun, Nodari
author_sort Naumenko, Krystyna
collection PubMed
description Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent.
format Online
Article
Text
id pubmed-10319835
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-103198352023-07-06 Antiviral activity of silver nanoparticles against the influenza A virus Naumenko, Krystyna Zahorodnia, Svitlana Pop, Calin V. Rizun, Nodari J Virus Erad Original Research Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent. Elsevier 2023-06-10 /pmc/articles/PMC10319835/ /pubmed/37416089 http://dx.doi.org/10.1016/j.jve.2023.100330 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Naumenko, Krystyna
Zahorodnia, Svitlana
Pop, Calin V.
Rizun, Nodari
Antiviral activity of silver nanoparticles against the influenza A virus
title Antiviral activity of silver nanoparticles against the influenza A virus
title_full Antiviral activity of silver nanoparticles against the influenza A virus
title_fullStr Antiviral activity of silver nanoparticles against the influenza A virus
title_full_unstemmed Antiviral activity of silver nanoparticles against the influenza A virus
title_short Antiviral activity of silver nanoparticles against the influenza A virus
title_sort antiviral activity of silver nanoparticles against the influenza a virus
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319835/
https://www.ncbi.nlm.nih.gov/pubmed/37416089
http://dx.doi.org/10.1016/j.jve.2023.100330
work_keys_str_mv AT naumenkokrystyna antiviralactivityofsilvernanoparticlesagainsttheinfluenzaavirus
AT zahorodniasvitlana antiviralactivityofsilvernanoparticlesagainsttheinfluenzaavirus
AT popcalinv antiviralactivityofsilvernanoparticlesagainsttheinfluenzaavirus
AT rizunnodari antiviralactivityofsilvernanoparticlesagainsttheinfluenzaavirus