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Antiviral activity of silver nanoparticles against the influenza A virus
Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319835/ https://www.ncbi.nlm.nih.gov/pubmed/37416089 http://dx.doi.org/10.1016/j.jve.2023.100330 |
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author | Naumenko, Krystyna Zahorodnia, Svitlana Pop, Calin V. Rizun, Nodari |
author_facet | Naumenko, Krystyna Zahorodnia, Svitlana Pop, Calin V. Rizun, Nodari |
author_sort | Naumenko, Krystyna |
collection | PubMed |
description | Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent. |
format | Online Article Text |
id | pubmed-10319835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-103198352023-07-06 Antiviral activity of silver nanoparticles against the influenza A virus Naumenko, Krystyna Zahorodnia, Svitlana Pop, Calin V. Rizun, Nodari J Virus Erad Original Research Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent. Elsevier 2023-06-10 /pmc/articles/PMC10319835/ /pubmed/37416089 http://dx.doi.org/10.1016/j.jve.2023.100330 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Naumenko, Krystyna Zahorodnia, Svitlana Pop, Calin V. Rizun, Nodari Antiviral activity of silver nanoparticles against the influenza A virus |
title | Antiviral activity of silver nanoparticles against the influenza A virus |
title_full | Antiviral activity of silver nanoparticles against the influenza A virus |
title_fullStr | Antiviral activity of silver nanoparticles against the influenza A virus |
title_full_unstemmed | Antiviral activity of silver nanoparticles against the influenza A virus |
title_short | Antiviral activity of silver nanoparticles against the influenza A virus |
title_sort | antiviral activity of silver nanoparticles against the influenza a virus |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319835/ https://www.ncbi.nlm.nih.gov/pubmed/37416089 http://dx.doi.org/10.1016/j.jve.2023.100330 |
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