Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning

OBJECTIVE: Norepinephrine stimulates the adipose tissue thermogenic program through a β-adrenergic receptor (βAR)–cyclic adenosine monophosphate (cAMP)–protein kinase A (PKA) signaling cascade. We discovered that a noncanonical activation of the mechanistic target of rapamycin complex 1 (mTORC1) by...

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Detalles Bibliográficos
Autores principales: Shi, Fubiao, de Fatima Silva, Flaviane, Liu, Dianxin, Patel, Hari U., Xu, Jonathan, Zhang, Wei, Türk, Clara, Krüger, Marcus, Collins, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319839/
https://www.ncbi.nlm.nih.gov/pubmed/37321371
http://dx.doi.org/10.1016/j.molmet.2023.101753

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