Altered muscle niche contributes to myogenic deficit in the D2-mdx model of severe DMD

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Lack of dystrophin expression is the underlying genetic basis for Duchenne muscular dystrophy (DMD). However, disease severity varies between patients, based on specific genetic modifiers. D2-mdx is a model for severe DMD that exhibits exacerbated muscle degeneration and failure to regenerate even i...

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Detalles Bibliográficos
Autores principales: Mázala, Davi A. G., Hindupur, Ravi, Moon, Young Jae, Shaikh, Fatima, Gamu, Iteoluwakishi H., Alladi, Dhruv, Panci, Georgiana, Weiss-Gayet, Michèle, Chazaud, Bénédicte, Partridge, Terence A., Novak, James S., Jaiswal, Jyoti K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319851/
https://www.ncbi.nlm.nih.gov/pubmed/37402716
http://dx.doi.org/10.1038/s41420-023-01503-0
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