Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes

SARS-CoV-2 spike protein (S) is structurally dynamic and has been observed by cryo-EM to adopt a variety of prefusion conformations that can be categorized as locked, closed, and open. S-trimers adopting locked conformations are tightly packed featuring structural elements incompatible with RBD in t...

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Detalles Bibliográficos
Autores principales: Zhang, Xixi, Li, Zimu, Zhang, Yanjun, Liu, Yutong, Wang, Jingjing, Liu, Banghui, Chen, Qiuluan, Wang, Qian, Fu, Lutang, Wang, Peiyi, Zhong, Xiaolin, Jin, Liang, Yan, Qihong, Chen, Ling, He, Jun, Zhao, Jincun, Xiong, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320017/
https://www.ncbi.nlm.nih.gov/pubmed/37402591
http://dx.doi.org/10.26508/lsa.202201796

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