Cargando…
OnTarget: in silico design of MiniPromoters for targeted delivery of expression
MiniPromoters, or compact promoters, are short DNA sequences that can drive expression in specific cells and tissues. While broadly useful, they are of high relevance to gene therapy due to their role in enabling precise control of where a therapeutic gene will be expressed. Here, we present OnTarge...
Autores principales: | Fornes, Oriol, Av-Shalom, Tamar V, Korecki, Andrea J, Farkas, Rachelle A, Arenillas, David J, Mathelier, Anthony, Simpson, Elizabeth M, Wasserman, Wyeth W |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320062/ https://www.ncbi.nlm.nih.gov/pubmed/37166953 http://dx.doi.org/10.1093/nar/gkad375 |
Ejemplares similares
-
Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells
por: Korecki, Andrea J., et al.
Publicado: (2021) -
New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina
por: Simpson, Elizabeth M., et al.
Publicado: (2019) -
PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina
por: Hickmott, Jack W, et al.
Publicado: (2016) -
rAAV-compatible MiniPromoters for restricted expression in the brain and eye
por: de Leeuw, Charles N., et al.
Publicado: (2016) -
Targeted CNS delivery using human MiniPromoters and demonstrated compatibility with adeno-associated viral vectors
por: de Leeuw, Charles N, et al.
Publicado: (2014)