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ARMADiLLO: a web server for analyzing antibody mutation probabilities

Antibodies are generated by B cells that evolve receptor specificity to pathogens through rounds of mutation and selection in a process called affinity maturation. Somatic hypermutation is mediated by an enzyme with DNA sequence context-dependent targeting and substitution resulting in variable prob...

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Detalles Bibliográficos
Autores principales: Martin Beem, Joshua S, Venkatayogi, Sravani, Haynes, Barton F, Wiehe, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320107/
https://www.ncbi.nlm.nih.gov/pubmed/37260077
http://dx.doi.org/10.1093/nar/gkad398