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ARMADiLLO: a web server for analyzing antibody mutation probabilities
Antibodies are generated by B cells that evolve receptor specificity to pathogens through rounds of mutation and selection in a process called affinity maturation. Somatic hypermutation is mediated by an enzyme with DNA sequence context-dependent targeting and substitution resulting in variable prob...
Autores principales: | Martin Beem, Joshua S, Venkatayogi, Sravani, Haynes, Barton F, Wiehe, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320107/ https://www.ncbi.nlm.nih.gov/pubmed/37260077 http://dx.doi.org/10.1093/nar/gkad398 |
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