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Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes

The Genome Context Viewer is a web application for identifying, aligning, and visualizing genomic regions based on their micro and macrosyntenic structures. By using functional elements such as gene annotations as the unit of search and comparison, the Genome Context Viewer can compute and display r...

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Detalles Bibliográficos
Autores principales: Cleary, Alan M, Farmer, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320139/
https://www.ncbi.nlm.nih.gov/pubmed/37207325
http://dx.doi.org/10.1093/nar/gkad391
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author Cleary, Alan M
Farmer, Andrew D
author_facet Cleary, Alan M
Farmer, Andrew D
author_sort Cleary, Alan M
collection PubMed
description The Genome Context Viewer is a web application for identifying, aligning, and visualizing genomic regions based on their micro and macrosyntenic structures. By using functional elements such as gene annotations as the unit of search and comparison, the Genome Context Viewer can compute and display relationships between regions across many assemblies from federated data sources in real-time, enabling users to rapidly explore multiple annotated genomes and identify divergence and structural events that can help provide insight into evolutionary mechanisms associated with functional consequences. In this work, we introduce version 2 of the Genome Context Viewer and highlight new features that enhance usability, performance, and ease of deployment.
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spelling pubmed-103201392023-07-06 Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes Cleary, Alan M Farmer, Andrew D Nucleic Acids Res Web Server Issue The Genome Context Viewer is a web application for identifying, aligning, and visualizing genomic regions based on their micro and macrosyntenic structures. By using functional elements such as gene annotations as the unit of search and comparison, the Genome Context Viewer can compute and display relationships between regions across many assemblies from federated data sources in real-time, enabling users to rapidly explore multiple annotated genomes and identify divergence and structural events that can help provide insight into evolutionary mechanisms associated with functional consequences. In this work, we introduce version 2 of the Genome Context Viewer and highlight new features that enhance usability, performance, and ease of deployment. Oxford University Press 2023-05-19 /pmc/articles/PMC10320139/ /pubmed/37207325 http://dx.doi.org/10.1093/nar/gkad391 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Web Server Issue
Cleary, Alan M
Farmer, Andrew D
Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes
title Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes
title_full Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes
title_fullStr Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes
title_full_unstemmed Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes
title_short Genome Context Viewer (GCV) version 2: enhanced visual exploration of multiple annotated genomes
title_sort genome context viewer (gcv) version 2: enhanced visual exploration of multiple annotated genomes
topic Web Server Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320139/
https://www.ncbi.nlm.nih.gov/pubmed/37207325
http://dx.doi.org/10.1093/nar/gkad391
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