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The potential therapeutic regimen for overcoming resistance to osimertinib due to rare mutations in NSCLC

The mechanisms of osimertinib resistance have not been well characterized. We conducted next-generation sequencing to recognize novel resistance mechanism and used cell line-derived xenograft (CDX) and patient-derived xenograft (PDX) models to evaluate the anti-proliferative effects of aspirin in vi...

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Detalles Bibliográficos
Autores principales:	Han, Rui, Lin, Caiyu, Zhang, Chong, Kang, Jun, Lu, Conghua, Zhang, Yiming, Wang, Yubo, Hu, Chen, He, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320197/ https://www.ncbi.nlm.nih.gov/pubmed/37416479 http://dx.doi.org/10.1016/j.isci.2023.107105

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