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Bmal1 downregulation leads to diabetic cardiomyopathy by promoting Bcl2/IP3R-mediated mitochondrial Ca(2+) overload

Brain and muscle arnt-like protein 1 (Bmal1) is a crucial transcription factor, regulating circadian rhythm and involved in multiple heart diseases. However, it is unknown whether Bmal1 promotes diabetic cardiomyopathy (DCM) pathogenesis. The objective of this investigation was to ascertain the vita...

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Detalles Bibliográficos
Autores principales:	Zhang, Nannan, Yu, Hao, Liu, Tianzi, Zhou, Zihao, Feng, Bin, Wang, Yao, Qian, Zhiyong, Hou, Xiaofeng, Zou, Jiangang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320280/ https://www.ncbi.nlm.nih.gov/pubmed/37356134 http://dx.doi.org/10.1016/j.redox.2023.102788

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