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Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis

Background: The Kilifi Health and Demographic Surveillance System (KHDSS) was established in 2000 to define the incidence and prevalence of local diseases and evaluate the impact of community-based interventions. KHDSS morbidity data have been reported comprehensively but mortality has not been desc...

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Autores principales: Otiende, Mark, Bauni, Evasius, Nyaguara, Amek, Amadi, David, Nyundo, Christopher, Tsory, Emmanuel, Walumbe, David, Kinuthia, Michael, Kihuha, Norbert, Kahindi, Michael, Nyutu, Gideon, Moisi, Jennifer, Deribew, Amare, Agweyu, Ambrose, Marsh, Kevin, Tsofa, Benjamin, Bejon, Philip, Bottomley, Christian, Williams, Thomas N., Scott, J. Anthony G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320326/
https://www.ncbi.nlm.nih.gov/pubmed/37416502
http://dx.doi.org/10.12688/wellcomeopenres.17307.2
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author Otiende, Mark
Bauni, Evasius
Nyaguara, Amek
Amadi, David
Nyundo, Christopher
Tsory, Emmanuel
Walumbe, David
Kinuthia, Michael
Kihuha, Norbert
Kahindi, Michael
Nyutu, Gideon
Moisi, Jennifer
Deribew, Amare
Agweyu, Ambrose
Marsh, Kevin
Tsofa, Benjamin
Bejon, Philip
Bottomley, Christian
Williams, Thomas N.
Scott, J. Anthony G.
author_facet Otiende, Mark
Bauni, Evasius
Nyaguara, Amek
Amadi, David
Nyundo, Christopher
Tsory, Emmanuel
Walumbe, David
Kinuthia, Michael
Kihuha, Norbert
Kahindi, Michael
Nyutu, Gideon
Moisi, Jennifer
Deribew, Amare
Agweyu, Ambrose
Marsh, Kevin
Tsofa, Benjamin
Bejon, Philip
Bottomley, Christian
Williams, Thomas N.
Scott, J. Anthony G.
author_sort Otiende, Mark
collection PubMed
description Background: The Kilifi Health and Demographic Surveillance System (KHDSS) was established in 2000 to define the incidence and prevalence of local diseases and evaluate the impact of community-based interventions. KHDSS morbidity data have been reported comprehensively but mortality has not been described. This analysis describes mortality in the KHDSS over 16 years. Methods: We calculated mortality rates from 2003–2018 in four intervals of equal duration and assessed differences in mortality across these intervals by age and sex. We calculated the period survival function and median survival using the Kaplan–Meier method and mean life expectancies using abridged life tables. We estimated trend and seasonality by decomposing a time series of monthly mortality rates. We used choropleth maps and random-effects Poisson regression to investigate geographical heterogeneity. Results: Mortality declined by 36% overall between 2003–2018 and by 59% in children aged <5 years. Most of the decline occurred between 2003 and 2006. Among adults, the greatest decline (49%) was observed in those aged 15–54 years. Life expectancy at birth increased by 12 years. Females outlived males by 6 years. Seasonality was only evident in the 1–4 year age group in the first four years. Geographical variation in mortality was ±10% of the median value and did not change over time. Conclusions: Between 2003 and 2018, mortality among children and young adults has improved substantially. The steep decline in 2003–2006 followed by a much slower reduction thereafter suggests improvements in health and wellbeing have plateaued in the last 12 years. However, there is substantial inequality in mortality experience by geographical location.
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spelling pubmed-103203262023-07-06 Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis Otiende, Mark Bauni, Evasius Nyaguara, Amek Amadi, David Nyundo, Christopher Tsory, Emmanuel Walumbe, David Kinuthia, Michael Kihuha, Norbert Kahindi, Michael Nyutu, Gideon Moisi, Jennifer Deribew, Amare Agweyu, Ambrose Marsh, Kevin Tsofa, Benjamin Bejon, Philip Bottomley, Christian Williams, Thomas N. Scott, J. Anthony G. Wellcome Open Res Research Article Background: The Kilifi Health and Demographic Surveillance System (KHDSS) was established in 2000 to define the incidence and prevalence of local diseases and evaluate the impact of community-based interventions. KHDSS morbidity data have been reported comprehensively but mortality has not been described. This analysis describes mortality in the KHDSS over 16 years. Methods: We calculated mortality rates from 2003–2018 in four intervals of equal duration and assessed differences in mortality across these intervals by age and sex. We calculated the period survival function and median survival using the Kaplan–Meier method and mean life expectancies using abridged life tables. We estimated trend and seasonality by decomposing a time series of monthly mortality rates. We used choropleth maps and random-effects Poisson regression to investigate geographical heterogeneity. Results: Mortality declined by 36% overall between 2003–2018 and by 59% in children aged <5 years. Most of the decline occurred between 2003 and 2006. Among adults, the greatest decline (49%) was observed in those aged 15–54 years. Life expectancy at birth increased by 12 years. Females outlived males by 6 years. Seasonality was only evident in the 1–4 year age group in the first four years. Geographical variation in mortality was ±10% of the median value and did not change over time. Conclusions: Between 2003 and 2018, mortality among children and young adults has improved substantially. The steep decline in 2003–2006 followed by a much slower reduction thereafter suggests improvements in health and wellbeing have plateaued in the last 12 years. However, there is substantial inequality in mortality experience by geographical location. F1000 Research Limited 2023-02-17 /pmc/articles/PMC10320326/ /pubmed/37416502 http://dx.doi.org/10.12688/wellcomeopenres.17307.2 Text en Copyright: © 2023 Otiende M et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Otiende, Mark
Bauni, Evasius
Nyaguara, Amek
Amadi, David
Nyundo, Christopher
Tsory, Emmanuel
Walumbe, David
Kinuthia, Michael
Kihuha, Norbert
Kahindi, Michael
Nyutu, Gideon
Moisi, Jennifer
Deribew, Amare
Agweyu, Ambrose
Marsh, Kevin
Tsofa, Benjamin
Bejon, Philip
Bottomley, Christian
Williams, Thomas N.
Scott, J. Anthony G.
Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis
title Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis
title_full Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis
title_fullStr Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis
title_full_unstemmed Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis
title_short Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis
title_sort mortality in rural coastal kenya measured using the kilifi health and demographic surveillance system: a 16-year descriptive analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320326/
https://www.ncbi.nlm.nih.gov/pubmed/37416502
http://dx.doi.org/10.12688/wellcomeopenres.17307.2
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