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Molecular insights into LINC complex architecture through the crystal structure of a luminal trimeric coiled-coil domain of SUN1

The LINC complex, consisting of interacting SUN and KASH proteins, mechanically couples nuclear contents to the cytoskeleton. In meiosis, the LINC complex transmits microtubule-generated forces to chromosome ends, driving the rapid chromosome movements that are necessary for synapsis and crossing ov...

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Detalles Bibliográficos
Autores principales:	Gurusaran, Manickam, Biemans, Jelle J., Wood, Christopher W., Davies, Owen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320395/ https://www.ncbi.nlm.nih.gov/pubmed/37416798 http://dx.doi.org/10.3389/fcell.2023.1144277

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