Inferred Immune-Cell Activity Is an Independent Predictor of HER2-Negative Breast Cancer Prognosis and Response to Paclitaxel-Based Therapy in the GeparSepto Trial

PURPOSE: Tumor microenvironment (TME) immune markers have been correlated with both response to neoadjuvant therapy and prognosis in patients with breast cancer. Here, immune-cell activity of breast cancer tumors was inferred by expression-based analysis to determine if it is prognostic and/or predi...

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Detalles Bibliográficos
Autores principales: Fasching, Peter A., Szeto, Christopher, Denkert, Carsten, Benz, Stephen, Weber, Karsten, Spilman, Patricia, Budczies, Jan, Schneeweiss, Andreas, Stickeler, Elmar, Schmatloch, Sabine, Jackisch, Christian, Karn, Thomas, Sinn, Hans Peter, Warm, Mathias, van Mackelenbergh, Marion, Rabizadeh, Shahrooz, Schem, Christian, Heinmöller, Ernst, Mueller, Volkmar, Marmé, Frederik, Soon-Shiong, Patrick, Nekljudova, Valentina, Untch, Michael, Loibl, Sibylle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320466/
https://www.ncbi.nlm.nih.gov/pubmed/37014668
http://dx.doi.org/10.1158/1078-0432.CCR-22-2213

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