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Regulation of PD-L1 Trafficking from Synthesis to Degradation

Programmed death-ligand 1 (PD-L1) is a transmembrane ligand for the programmed cell death protein 1 (PD-1), a receptor that inhibits T-cell activity. The PD-L1/PD-1 immune checkpoint axis has been successfully targeted to enhance antitumor immune responses. Tethering PD-L1 to the membrane spatially...

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Detalles Bibliográficos
Autores principales:	Lemma, Eyoel Yemanaberhan, Letian, Anudari, Altorki, Nasser K., McGraw, Timothy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320477/ https://www.ncbi.nlm.nih.gov/pubmed/37290119 http://dx.doi.org/10.1158/2326-6066.CIR-22-0953

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