Cargando…

TNF ( ΔARE ) Pigs: A Translational Crohn’s Disease Model

BACKGROUND AND AIMS: Crohn’s disease [CD] is a major subtype of inflammatory bowel diseases [IBD] with increasing incidence and prevalence. Results of studies using available small and large animal models are often poorly translatable to patients, and few CD models show small intestinal pathology. D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Winogrodzki, Thomas, Metwaly, Amira, Grodziecki, Alessandro, Liang, Wei, Klinger, Bernhard, Flisikowska, Tatiana, Fischer, Konrad, Flisikowski, Krzysztof, Steiger, Katja, Haller, Dirk, Schnieke, Angelika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320488/ https://www.ncbi.nlm.nih.gov/pubmed/36821422 http://dx.doi.org/10.1093/ecco-jcc/jjad034

Ejemplares similares

A tissue- and gender-specific regulation of the SARS-CoV-2 receptor ACE2 by p53 in pigs
por: Zhang, Yue, et al.
Publicado: (2021)

Wild-type APC Influences the Severity of Familial Adenomatous Polyposis
por: Flisikowski, Krzysztof, et al.
Publicado: (2021)

Dual Fluorescent Reporter Pig for Cre Recombination: Transgene Placement at the ROSA26 Locus
por: Li, Shun, et al.
Publicado: (2014)

Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA
por: Niu, Guanglin, et al.
Publicado: (2021)

The Missing Link: Cre Pigs for Cancer Research
por: Kalla, Daniela, et al.
Publicado: (2021)

Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma
por: Niu, Guanglin, et al.
Publicado: (2021)

Inactivation and Inducible Oncogenic Mutation of p53 in Gene Targeted Pigs
por: Leuchs, Simon, et al.
Publicado: (2012)

Cas9-expressing chickens and pigs as resources for genome editing in livestock
por: Rieblinger, Beate, et al.
Publicado: (2021)

Altered microRNA profiles during early colon adenoma progression in a porcine model of familial adenomatous polyposis
por: Stachowiak, Monika, et al.
Publicado: (2017)

Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing
por: Fischer, Konrad, et al.
Publicado: (2016)

Role of Methylation in Period2 (PER2) Transcription in the Context of the Presence or Absence of Light Signals: Natural and Chemical—Studies on the Pig Model
por: Gilun, Przemysław, et al.
Publicado: (2021)

Detection of porcine cytomegalovirus, a roseolovirus, in pig ovaries and follicular fluid: implications for somatic cells nuclear transfer, cloning and xenotransplantation
por: Hansen, Sabrina, et al.
Publicado: (2023)

Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression
por: Flisikowska, Tatiana, et al.
Publicado: (2017)

A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies
por: Flisikowska, Tatiana, et al.
Publicado: (2022)

Analysis of allele-specific expression of seven candidate genes involved in lipid metabolism in pig skeletal muscle and fat tissues reveals allelic imbalance of ACACA, LEP, SCD, and TNF
por: Stachowiak, Monika, et al.
Publicado: (2019)

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set
por: Kurome, Mayuko, et al.
Publicado: (2013)

Xenotransplantation becoming reality
por: Fischer, Konrad, et al.
Publicado: (2022)

How genome editing changed the world of large animal research
por: Fischer, Konrad, et al.
Publicado: (2023)

Genetically Engineered Pigs to Study Cancer
por: Kalla, Daniela, et al.
Publicado: (2020)

Genetically engineered pigs as models for human disease
por: Perleberg, Carolin, et al.
Publicado: (2018)

Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle
por: Pausch, Hubert, et al.
Publicado: (2015)

Advances in single-cell sequencing: insights from organ transplantation
por: Wang, Ying, et al.
Publicado: (2021)

A porcine model of osteosarcoma
por: Saalfrank, A, et al.
Publicado: (2016)

In frame exon skipping in UBE3B is associated with developmental disorders and increased mortality in cattle
por: Venhoranta, Heli, et al.
Publicado: (2014)

A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle
por: Schwarzenbacher, Hermann, et al.
Publicado: (2016)

Microbial Signals Link Westernized Diet to Metabolic Inflammation: More Evidence to Resolve Controversies
por: Metwaly, Amira, et al.
Publicado: (2019)

Bitter Peptides YFYPEL, VAPFPEVF, and YQEPVLGPVRGPFPIIV, Released during Gastric Digestion of Casein, Stimulate Mechanisms of Gastric Acid Secretion via Bitter Taste Receptors TAS2R16 and TAS2R38
por: Richter, Phil, et al.
Publicado: (2022)

Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn’s disease recurrence
por: Khaloian, Sevana, et al.
Publicado: (2020)

Anti-TNF Therapy in Crohn’s Disease
por: Adegbola, Samuel O., et al.
Publicado: (2018)

Selective Targeting of Tumour Necrosis Factor Receptor 1 Induces Stable Protection from Crohn’s-Like Ileitis in TNF(ΔARE) Mice
por: Chakraborty, Rajrupa, et al.
Publicado: (2021)

Integrated microbiota and metabolite profiles link Crohn’s disease to sulfur metabolism
por: Metwaly, Amira, et al.
Publicado: (2020)

Preclinical Evaluation of a Microwave-Based Accessory Device for Colonoscopy in an In Vivo Porcine Model with Colorectal Polyps
por: Garrido, Alejandra, et al.
Publicado: (2023)

Efficient Immunoglobulin Gene Disruption and Targeted Replacement in Rabbit Using Zinc Finger Nucleases
por: Flisikowska, Tatiana, et al.
Publicado: (2011)

The influence of anti-TNF therapy on the magnetic resonance enterographic parameters of Crohn’s disease activity
por: Eder, Piotr, et al.
Publicado: (2015)

Correction to: Elevated circulating Hsp70 levels are correlative for malignancies in different mammalian species
por: Salvermoser, Lukas, et al.
Publicado: (2022)

Elevated circulating Hsp70 levels are correlative for malignancies in different mammalian species
por: Salvermoser, Lukas, et al.
Publicado: (2022)

Modeling microbiota-associated human diseases: from minimal models to complex systems
por: Aguanno, Doriane, et al.
Publicado: (2022)

Anti-TNF Exposure during Pregnancy in Crohn's Disease Patients
por: Silva, Elen Farinelli de Campos, et al.
Publicado: (2018)

PREDICTIVE FACTORS FOR LOSS OF RESPONSE TO ANTI-TNF IN CROHN’S DISEASE
por: dos SANTOS, Byanca Rossetti Moreira, et al.
Publicado: (2020)

Is Autologous Fecal Microbiota Transfer after Exclusive Enteral Nutrition in Pediatric Crohn’s Disease Patients Rational and Feasible? Data from a Feasibility Test
por: Hoelz, Hannes, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kfp6otk12h0oh0b7lkbu6c8mou