High-throughput longitudinal electrophysiology screening of mature chamber-specific hiPSC-CMs using optical mapping

hiPSC-CMs are being considered by the Food and Drug Administration and other regulatory agencies for in vitro cardiotoxicity screening to provide human-relevant safety data. Widespread adoption of hiPSC-CMs in regulatory and academic science is limited by the immature, fetal-like phenotype of the ce...

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Detalles Bibliográficos
Autores principales: Allan, Andrew, Creech, Jeffery, Hausner, Christian, Krajcarski, Peyton, Gunawan, Bianca, Poulin, Noah, Kozlowski, Paul, Clark, Christopher Wayne, Dow, Rachel, Saraithong, Prakaimuk, Mair, Devin B., Block, Travis, Monteiro da Rocha, Andre, Kim, Deok-Ho, Herron, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320609/
https://www.ncbi.nlm.nih.gov/pubmed/37416454
http://dx.doi.org/10.1016/j.isci.2023.107142

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