Cargando…

ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding

Foamy and inflammatory macrophages play pathogenic roles in metabolic disorders. However, the mechanisms that promote foamy and inflammatory macrophage phenotypes under acute-high-fat feeding (AHFF) remain elusive. Herein, we investigated the role of acyl-CoA synthetase-1 (ACSL1) in favoring the foa...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Rashed, Fatema, Haddad, Dania, Al Madhoun, Ashraf, Sindhu, Sardar, Jacob, Texy, Kochumon, Shihab, Obeid, Lina M., Al-Mulla, Fahd, Hannun, Yusuf A., Ahmad, Rasheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320618/
https://www.ncbi.nlm.nih.gov/pubmed/37416456
http://dx.doi.org/10.1016/j.isci.2023.107145