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ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding
Foamy and inflammatory macrophages play pathogenic roles in metabolic disorders. However, the mechanisms that promote foamy and inflammatory macrophage phenotypes under acute-high-fat feeding (AHFF) remain elusive. Herein, we investigated the role of acyl-CoA synthetase-1 (ACSL1) in favoring the foa...
Autores principales: | Al-Rashed, Fatema, Haddad, Dania, Al Madhoun, Ashraf, Sindhu, Sardar, Jacob, Texy, Kochumon, Shihab, Obeid, Lina M., Al-Mulla, Fahd, Hannun, Yusuf A., Ahmad, Rasheed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320618/ https://www.ncbi.nlm.nih.gov/pubmed/37416456 http://dx.doi.org/10.1016/j.isci.2023.107145 |
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