KRT17 Promotes T-lymphocyte Infiltration Through the YTHDF2–CXCL10 Axis in Colorectal Cancer

Poor infiltration of T lymphocytes has been regarded as a crucial mechanism of tumor immune escape. Here, we demonstrate a protective role of KRT17 in colorectal cancer, where KRT17 reversed the tumor immunosuppressive microenvironment by increasing T-lymphocyte infiltration. High-throughput RNA seq...

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Detalles Bibliográficos
Autores principales: Liang, Wenfeng, Liu, Huashan, Zeng, Ziwei, Liang, Zhenxing, Xie, Hao, Li, Wenxin, Xiong, Li, Liu, Zhihang, Chen, Mian, Jie, Haiqing, Zheng, Xiaobin, Huang, Liang, Kang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320689/
https://www.ncbi.nlm.nih.gov/pubmed/37129929
http://dx.doi.org/10.1158/2326-6066.CIR-22-0814

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