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Tetracycline-mediated fluorescence correlates with passage number and β-galactosidase activity in HeLa and HEK293T cells

We report data consistent with tetracycline-mediated fluorescence having the potential to be an effective marker of senescence in immortalised cells. HeLa cells that had previously undergone more than 20 passages were transiently transfected with a plasmid encoding a novel tetracycline-inducible tra...

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Detalles Bibliográficos
Autores principales: Redwood-Sawyerr, Chileab, Nesbeth, Darren N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320714/
https://www.ncbi.nlm.nih.gov/pubmed/37284818
http://dx.doi.org/10.1242/bio.059691