NOD2 in monocytes negatively regulates macrophage development through TNFalpha

OBJECTIVE: It is believed that intestinal recruitment of monocytes from Crohn’s Disease (CD) patients who carry NOD2 risk alleles may repeatedly give rise to recruitment of pathogenic macrophages. We investigated an alternative possibility that NOD2 may rather inhibit their differentiation from intr...

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Detalles Bibliográficos
Autores principales: Chauvin, Camille, Alvarez-Simon, Daniel, Radulovic, Katarina, Boulard, Olivier, Laine, William, Delacre, Myriam, Waldschmitt, Nadine, Segura, Elodie, Kluza, Jérome, Chamaillard, Mathias, Poulin, Lionel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320732/
https://www.ncbi.nlm.nih.gov/pubmed/37415975
http://dx.doi.org/10.3389/fimmu.2023.1181823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320732/
https://www.ncbi.nlm.nih.gov/pubmed/37415975
http://dx.doi.org/10.3389/fimmu.2023.1181823

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