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NOD2 in monocytes negatively regulates macrophage development through TNFalpha
OBJECTIVE: It is believed that intestinal recruitment of monocytes from Crohn’s Disease (CD) patients who carry NOD2 risk alleles may repeatedly give rise to recruitment of pathogenic macrophages. We investigated an alternative possibility that NOD2 may rather inhibit their differentiation from intr...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320732/ https://www.ncbi.nlm.nih.gov/pubmed/37415975 http://dx.doi.org/10.3389/fimmu.2023.1181823 |