A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence

Cellular senescence is a program of cell cycle arrest, apoptosis resistance, and cytokine release induced by stress exposure in metazoan cells. Landmark studies in laboratory mice have characterized a number of master senescence regulators, including p16(INK4a), p21, NF-κB, p53, and C/EBPβ. To disco...

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Detalles Bibliográficos
Autores principales: Kang, Taekyu, Moore, Emily C, Kopania, Emily E K, King, Christina D, Schilling, Birgit, Campisi, Judith, Good, Jeffrey M, Brem, Rachel B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320765/
https://www.ncbi.nlm.nih.gov/pubmed/37097016
http://dx.doi.org/10.1093/g3journal/jkad091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320765/
https://www.ncbi.nlm.nih.gov/pubmed/37097016
http://dx.doi.org/10.1093/g3journal/jkad091

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