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A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence
Cellular senescence is a program of cell cycle arrest, apoptosis resistance, and cytokine release induced by stress exposure in metazoan cells. Landmark studies in laboratory mice have characterized a number of master senescence regulators, including p16(INK4a), p21, NF-κB, p53, and C/EBPβ. To disco...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320765/ https://www.ncbi.nlm.nih.gov/pubmed/37097016 http://dx.doi.org/10.1093/g3journal/jkad091 |