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Molecular dynamics modelling of the interaction of a synthetic zinc-finger miniprotein with DNA

We report the modelling of the DNA complex of an artificial miniprotein composed of two zinc finger modules and an AT-hook linking peptide. The computational study provides for the first time a structural view of these types of complexes, dissecting interactions that are key to modulate their stabil...

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Detalles Bibliográficos
Autores principales: Rodriguez, Jessica, Battistini, Federica, Learte-Aymamí, Soraya, Orozco, Modesto, Mascareñas, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320839/
https://www.ncbi.nlm.nih.gov/pubmed/37415868
http://dx.doi.org/10.1039/d3cb00053b

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