Cargando…

The multivalent G-quadruplex (G4)-ligands MultiTASQs allow for versatile click chemistry-based investigations

Chemical biology hinges on multivalent molecular tools that can specifically interrogate and/or manipulate cellular circuitries from the inside. The success of many of these approaches relies on molecular tools that make it possible to visualize biological targets in cells and then isolate them for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rota Sperti, Francesco, Mitteaux, Jérémie, Zell, Joanna, Pipier, Angélique, Valverde, Ibai E., Monchaud, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320843/ https://www.ncbi.nlm.nih.gov/pubmed/37415864 http://dx.doi.org/10.1039/d3cb00009e

Ejemplares similares

Click-Chemistry-Based Biomimetic Ligands Efficiently Capture G-Quadruplexes In Vitro and Help Localize Them at DNA Damage Sites in Human Cells
por: Rota Sperti, Francesco, et al.
Publicado: (2022)

Side-by-side comparison of G-quadruplex (G4) capture efficiency of the antibody BG4 versus the small-molecule ligands TASQs
por: Feng, Yilong, et al.
Publicado: (2023)

Differential responses of neurons, astrocytes, and microglia to G-quadruplex stabilization
por: Tabor, Natalie, et al.
Publicado: (2021)

Conformation of G-quadruplex Controlled by Click Reaction
por: Xiao, Chao-Da, et al.
Publicado: (2020)

DNA folds threaten genetic stability and can be leveraged for chemotherapy
por: Zell, Joanna, et al.
Publicado: (2020)

CNBP controls transcription by unfolding DNA G-quadruplex structures
por: David, Aldana P, et al.
Publicado: (2019)

Selective RNAVersus DNA G-Quadruplex Targeting by In Situ Click Chemistry**
por: Di Antonio, Marco, et al.
Publicado: (2012)

Development of squaraine based G-quadruplex ligands using click chemistry
por: Zhang, Xin, et al.
Publicado: (2017)

G-quadruplexes mark alternative lengthening of telomeres
por: Yang, Sunny Y, et al.
Publicado: (2021)

Insights into how nucleotide supplements enhance the peroxidase-mimicking DNAzyme activity of the G-quadruplex/hemin system
por: Stefan, Loic, et al.
Publicado: (2012)

Interactions of small molecules with DNA junctions
por: McQuaid, Kane T, et al.
Publicado: (2022)

Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
por: Yang, Sunny Y., et al.
Publicado: (2018)

The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties
por: Cheng, Yu, et al.
Publicado: (2020)

Design and synthesis of multivalent neoglycoconjugates by click conjugations
por: Ding, Feiqing, et al.
Publicado: (2014)

Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands
por: Bossaert, Madeleine, et al.
Publicado: (2021)

Toronto aortic stenosis quality of life questionnaire (TASQ): validation in TAVI patients
por: Styra, Rima, et al.
Publicado: (2020)

rG4detector, a novel RNA G-quadruplex predictor, uncovers their impact on stress granule formation
por: Turner, Maor, et al.
Publicado: (2022)

A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology
por: Hu, Ming-Hao, et al.
Publicado: (2015)

Synthesis and Evaluation of a Rationally Designed Click-Based Library for G-Quadruplex Selective DNA Photocleavage
por: McBrayer, Dominic, et al.
Publicado: (2015)

The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
por: Lyonnais, Sébastien, et al.
Publicado: (2017)

Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design
por: Haase, Linn, et al.
Publicado: (2020)

Concept confirmation of the Treatment Administration Satisfaction Questionnaire (TASQ) in rare paroxysmal nocturnal hemoglobinuria
por: Doll, Helen, et al.
Publicado: (2021)

Trial protocol for the validation of the ‘Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire’ in patients undergoing surgical aortic valve replacement (SAVR) or transfemoral (TF) transcatheter aortic valve implantation (TAVI): the TASQ registry
por: Frank, Derk, et al.
Publicado: (2019)

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
por: Ruggiero, Emanuela, et al.
Publicado: (2018)

Detection of CpG Methylation in G-Quadruplex Forming Sequences Using G-Quadruplex Ligands
por: Hasegawa, Hijiri, et al.
Publicado: (2021)

G-quadruplexes and helicases
por: Mendoza, Oscar, et al.
Publicado: (2016)

G-Quadruplexes (GQU)
por: Haider, Shozeb, et al.
Publicado: (2018)

Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
por: Lyonnais, Sébastien, et al.
Publicado: (2017)

“One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition
por: Monchaud, David, et al.
Publicado: (2010)

G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders
por: Miglietta, Giulia, et al.
Publicado: (2020)

G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders
por: Miglietta, Giulia, et al.
Publicado: (2020)

G-Quadruplexes and Their Ligands: Biophysical Methods to Unravel G-Quadruplex/Ligand Interactions
por: Santos, Tiago, et al.
Publicado: (2021)

Pirh2-dependent DNA damage in neurons induced by the G-quadruplex ligand pyridostatin
por: Escarcega, Rocio Diaz, et al.
Publicado: (2023)

Exploded view of higher order G-quadruplex structures through click-chemistry assisted single-molecule mechanical unfolding
por: Selvam, Sangeetha, et al.
Publicado: (2016)

Programmable Nanoscaffolds That Control Ligand Display to a G-Protein-Coupled Receptor in Membranes To Allow Dissection of Multivalent Effects
por: Dix, Andrew V., et al.
Publicado: (2014)

Classification of G-Quadruplex DNA on the Basis of the Quadruplex Twist Angle and Planarity of G-Quartets
por: Reshetnikov, R.V., et al.
Publicado: (2010)

Characterization of G-Quadruplexes in Enterovirus A71 Genome and Their Interaction with G-Quadruplex Ligands
por: Lv, Lu, et al.
Publicado: (2022)

“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles
por: Granzhan, Anton, et al.
Publicado: (2010)

Stability of telomeric G-quadruplexes
por: Tran, Phong Lan Thao, et al.
Publicado: (2011)

G-Quadruplex Nucleic Acids
por: Eritja, Ramon, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_87n2t6hgab60f6t9qachaad91l