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Protocadherin 20 maintains intestinal barrier function to protect against Crohn’s disease by targeting ATF6
BACKGROUND: Intestinal barrier dysfunction plays a central role in the pathological onset of Crohn’s disease. We identify the cadherin superfamily member protocadherin 20 (PCDH20) as a crucial factor in Crohn’s disease. Here we describe the function of PCDH20 and its mechanisms in gut homeostasis, b...
Hlavní autoři: | , , , , , , , , , , , , , |
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Médium: | Online Článek Text |
Jazyk: | English |
Vydáno: |
BioMed Central
2023
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Témata: | |
On-line přístup: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320870/ https://www.ncbi.nlm.nih.gov/pubmed/37407995 http://dx.doi.org/10.1186/s13059-023-02991-0 |