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Methylmalonic acid promotes colorectal cancer progression via activation of Wnt/β-catenin pathway mediated epithelial–mesenchymal transition

BACKGROUND: It has been manifested in several studies that age-related metabolic reprogramming is associated with tumor progression, in particular, colorectal cancer (CRC). Here we investigated the role of upregulated metabolites of the aged serum, including methylmalonic acid (MMA), phosphoenolpyru...

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Detalles Bibliográficos
Autores principales: Hu, Chunhua, Ye, Mujie, Bai, Jianan, Liu, Pengfei, Lu, Feiyu, Chen, Jinhao, Yu, Ping, Chen, Tiaotiao, Shi, Xiaoting, Tang, Qiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320877/
https://www.ncbi.nlm.nih.gov/pubmed/37403090
http://dx.doi.org/10.1186/s12935-023-02973-z