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Methylmalonic acid promotes colorectal cancer progression via activation of Wnt/β-catenin pathway mediated epithelial–mesenchymal transition
BACKGROUND: It has been manifested in several studies that age-related metabolic reprogramming is associated with tumor progression, in particular, colorectal cancer (CRC). Here we investigated the role of upregulated metabolites of the aged serum, including methylmalonic acid (MMA), phosphoenolpyru...
Autores principales: | Hu, Chunhua, Ye, Mujie, Bai, Jianan, Liu, Pengfei, Lu, Feiyu, Chen, Jinhao, Yu, Ping, Chen, Tiaotiao, Shi, Xiaoting, Tang, Qiyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320877/ https://www.ncbi.nlm.nih.gov/pubmed/37403090 http://dx.doi.org/10.1186/s12935-023-02973-z |
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