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Multi-scale systems genomics analysis predicts pathways, cell types, and drug targets involved in normative variation in peri-adolescent human cognition

An open challenge in human genetics is to better understand the systems-level impact of genotype variation on developmental cognition. To characterize the genetic underpinnings of peri-adolescent cognition, we performed genotype–phenotype and systems analysis for binarized accuracy in nine cognitive...

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Detalles Bibliográficos
Autores principales: Pai, Shraddha, Hui, Shirley, Weber, Philipp, Narayan, Soumil, Whitley, Owen, Li, Peipei, Labrie, Viviane, Baumbach, Jan, Wheeler, Anne L, Bader, Gary D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321094/
https://www.ncbi.nlm.nih.gov/pubmed/37106565
http://dx.doi.org/10.1093/cercor/bhad142