Sialic acid: an attractive biomarker with promising biomedical applications

This broad, narrative review highlights the roles of sialic acids as acidic sugars found on cellular membranes. The role of sialic acids in cellular communication and development has been well established. Recently, attention has turned to the fundamental role of sialic acids in many diseases, inclu...

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Autores principales: Doostkam, Aida, Malekmakan, Leila, Hosseinpour, Alireza, Janfeshan, Sahar, Roozbeh, Jamshid, Masjedi, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321195/
https://www.ncbi.nlm.nih.gov/pubmed/37551166
http://dx.doi.org/10.2478/abm-2022-0020
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author Doostkam, Aida
Malekmakan, Leila
Hosseinpour, Alireza
Janfeshan, Sahar
Roozbeh, Jamshid
Masjedi, Fatemeh
author_facet Doostkam, Aida
Malekmakan, Leila
Hosseinpour, Alireza
Janfeshan, Sahar
Roozbeh, Jamshid
Masjedi, Fatemeh
author_sort Doostkam, Aida
collection PubMed
description This broad, narrative review highlights the roles of sialic acids as acidic sugars found on cellular membranes. The role of sialic acids in cellular communication and development has been well established. Recently, attention has turned to the fundamental role of sialic acids in many diseases, including viral infections, cardiovascular diseases, neurological disorders, diabetic nephropathy, and malignancies. Sialic acid may be a target for developing new drugs to treat various cancers and inflammatory processes. We recommend the routine measurement of serum sialic acid as a sensitive inflammatory marker in various diseases.
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spelling pubmed-103211952023-08-07 Sialic acid: an attractive biomarker with promising biomedical applications Doostkam, Aida Malekmakan, Leila Hosseinpour, Alireza Janfeshan, Sahar Roozbeh, Jamshid Masjedi, Fatemeh Asian Biomed (Res Rev News) Review This broad, narrative review highlights the roles of sialic acids as acidic sugars found on cellular membranes. The role of sialic acids in cellular communication and development has been well established. Recently, attention has turned to the fundamental role of sialic acids in many diseases, including viral infections, cardiovascular diseases, neurological disorders, diabetic nephropathy, and malignancies. Sialic acid may be a target for developing new drugs to treat various cancers and inflammatory processes. We recommend the routine measurement of serum sialic acid as a sensitive inflammatory marker in various diseases. Sciendo 2022-08-31 /pmc/articles/PMC10321195/ /pubmed/37551166 http://dx.doi.org/10.2478/abm-2022-0020 Text en © 2022 Aida Doostkam et al., published by Sciendo https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Review
Doostkam, Aida
Malekmakan, Leila
Hosseinpour, Alireza
Janfeshan, Sahar
Roozbeh, Jamshid
Masjedi, Fatemeh
Sialic acid: an attractive biomarker with promising biomedical applications
title Sialic acid: an attractive biomarker with promising biomedical applications
title_full Sialic acid: an attractive biomarker with promising biomedical applications
title_fullStr Sialic acid: an attractive biomarker with promising biomedical applications
title_full_unstemmed Sialic acid: an attractive biomarker with promising biomedical applications
title_short Sialic acid: an attractive biomarker with promising biomedical applications
title_sort sialic acid: an attractive biomarker with promising biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321195/
https://www.ncbi.nlm.nih.gov/pubmed/37551166
http://dx.doi.org/10.2478/abm-2022-0020
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AT roozbehjamshid sialicacidanattractivebiomarkerwithpromisingbiomedicalapplications
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