Cargando…

Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette

Tuberculosis is caused by Mycobacterium tuberculosis. Tuberculosis of the central nervous system is common and manifestations include meningeal and intraparenchymal diseases. However, intraventricular tuberculous abscess is a rare manifestation of intracranial tuberculous infection. We present a cas...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanafiah, Mohamad, Mukhari, Shahizon A Mohamed, Mustapha, Aida M, Mumin, Nazimah Ab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321223/
https://www.ncbi.nlm.nih.gov/pubmed/37551366
http://dx.doi.org/10.2478/abm-2021-0036
_version_ 1785068583068368896
author Hanafiah, Mohamad
Mukhari, Shahizon A Mohamed
Mustapha, Aida M
Mumin, Nazimah Ab
author_facet Hanafiah, Mohamad
Mukhari, Shahizon A Mohamed
Mustapha, Aida M
Mumin, Nazimah Ab
author_sort Hanafiah, Mohamad
collection PubMed
description Tuberculosis is caused by Mycobacterium tuberculosis. Tuberculosis of the central nervous system is common and manifestations include meningeal and intraparenchymal diseases. However, intraventricular tuberculous abscess is a rare manifestation of intracranial tuberculous infection. We present a case of an immunocompromised female patient with high-grade fever and signs of meningism. The computed tomography and magnetic resonance imaging (MRI) of the brain showed hydrocephalus with rim-enhancing lesion in the right lateral ventricle. The MRI demonstrated a hypointense signal on T1-weighted imaging, hyperintense signal on T2-weighted imaging, and mild restricted diffusion in diffusion-weighted imaging. She underwent emergency external ventricular drainage and frank pus was drained. Diagnosis of tuberculosis was made via polymerase chain reaction analysis and culture. Understanding the intracranial manifestation of neurotuberculosis is imperative to arrive at the diagnosis correctly and ensure prompt treatment.
format Online
Article
Text
id pubmed-10321223
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Sciendo
record_format MEDLINE/PubMed
spelling pubmed-103212232023-08-07 Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette Hanafiah, Mohamad Mukhari, Shahizon A Mohamed Mustapha, Aida M Mumin, Nazimah Ab Asian Biomed (Res Rev News) Clinical Vignette Tuberculosis is caused by Mycobacterium tuberculosis. Tuberculosis of the central nervous system is common and manifestations include meningeal and intraparenchymal diseases. However, intraventricular tuberculous abscess is a rare manifestation of intracranial tuberculous infection. We present a case of an immunocompromised female patient with high-grade fever and signs of meningism. The computed tomography and magnetic resonance imaging (MRI) of the brain showed hydrocephalus with rim-enhancing lesion in the right lateral ventricle. The MRI demonstrated a hypointense signal on T1-weighted imaging, hyperintense signal on T2-weighted imaging, and mild restricted diffusion in diffusion-weighted imaging. She underwent emergency external ventricular drainage and frank pus was drained. Diagnosis of tuberculosis was made via polymerase chain reaction analysis and culture. Understanding the intracranial manifestation of neurotuberculosis is imperative to arrive at the diagnosis correctly and ensure prompt treatment. Sciendo 2021-12-30 /pmc/articles/PMC10321223/ /pubmed/37551366 http://dx.doi.org/10.2478/abm-2021-0036 Text en © 2021 Mohamad Hanafiah et al., published by Sciendo https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Clinical Vignette
Hanafiah, Mohamad
Mukhari, Shahizon A Mohamed
Mustapha, Aida M
Mumin, Nazimah Ab
Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette
title Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette
title_full Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette
title_fullStr Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette
title_full_unstemmed Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette
title_short Intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette
title_sort intraventricular tuberculosis abscess in an immunocompromised patient: clinical vignette
topic Clinical Vignette
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321223/
https://www.ncbi.nlm.nih.gov/pubmed/37551366
http://dx.doi.org/10.2478/abm-2021-0036
work_keys_str_mv AT hanafiahmohamad intraventriculartuberculosisabscessinanimmunocompromisedpatientclinicalvignette
AT mukharishahizonamohamed intraventriculartuberculosisabscessinanimmunocompromisedpatientclinicalvignette
AT mustaphaaidam intraventriculartuberculosisabscessinanimmunocompromisedpatientclinicalvignette
AT muminnazimahab intraventriculartuberculosisabscessinanimmunocompromisedpatientclinicalvignette