The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein

Conformational diseases, such as Alzheimer, Parkinson and Huntington diseases, are part of a common class of neurological disorders characterized by the aggregation and progressive accumulation of proteins bearing aberrant conformations. Huntington disease (HD) has autosomal dominant inheritance and...

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Detalles Bibliográficos
Autores principales: Bonavita, R, Scerra, G, Di Martino, R, Nuzzo, S, Polishchuk, E, Di Gennaro, M, Williams, S V, Caporaso, M G, Caiazza, C, Polishchuk, R, D’Agostino, M, Fleming, A, Renna, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321397/
https://www.ncbi.nlm.nih.gov/pubmed/36971475
http://dx.doi.org/10.1093/hmg/ddad047

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