Reproducible Quantification of Unbound Fractions of Four Beta-Lactam Antibiotics: Ultrafiltration Versus Microdialysis of Spiked Healthy Donor Plasma

Ultrafiltration (UF) is a conventional method for isolating the protein-unbound plasma fractions of therapeutic drugs. However, the ideal UF conditions for specific compounds remain largely unexplored. By comparing UF-derived unbound concentrations with the corresponding results obtained using a ref...

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Detalles Bibliográficos
Autores principales: Beijer, Gustaf, Clarin, Leona, Östervall, Jennie, Barclay, Victoria, Eliasson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321508/
https://www.ncbi.nlm.nih.gov/pubmed/35971673
http://dx.doi.org/10.1097/FTD.0000000000001016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321508/
https://www.ncbi.nlm.nih.gov/pubmed/35971673
http://dx.doi.org/10.1097/FTD.0000000000001016

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