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Reproducible Quantification of Unbound Fractions of Four Beta-Lactam Antibiotics: Ultrafiltration Versus Microdialysis of Spiked Healthy Donor Plasma

Ultrafiltration (UF) is a conventional method for isolating the protein-unbound plasma fractions of therapeutic drugs. However, the ideal UF conditions for specific compounds remain largely unexplored. By comparing UF-derived unbound concentrations with the corresponding results obtained using a ref...

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Detalles Bibliográficos
Autores principales:	Beijer, Gustaf, Clarin, Leona, Östervall, Jennie, Barclay, Victoria, Eliasson, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Therapeutic Drug Monitoring 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321508/ https://www.ncbi.nlm.nih.gov/pubmed/35971673 http://dx.doi.org/10.1097/FTD.0000000000001016

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