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Functional LTCC-β(2)AR Complex Needs Caveolin-3 and Is Disrupted in Heart Failure

Beta-2 adrenergic receptors (β(2)ARs) but not beta-2 adrenergic receptors (β(1)ARs) form a functional complex with L-type Ca(2+) channels (LTCCs) on the cardiomyocyte membrane. However, how microdomain localization in the plasma membrane affects the function of these complexes is unknown. We aim to...

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Detalles Bibliográficos
Autores principales:	Sanchez-Alonso, Jose L., Fedele, Laura, Copier, Jaël S., Lucarelli, Carla, Mansfield, Catherine, Judina, Aleksandra, Houser, Steven R., Brand, Thomas, Gorelik, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321517/ https://www.ncbi.nlm.nih.gov/pubmed/37313722 http://dx.doi.org/10.1161/CIRCRESAHA.123.322508

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