Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma

Introduction: Asthma is a chronic disease of the airways that impairs normal breathing. The etiology of asthma is complex and involves multiple factors, including the environment and genetics, especially the distinct genetic architecture associated with ancestry. Compared to early-onset asthma, litt...

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Detalles Bibliográficos
Autores principales: Lee, Eunice Y., Choi, Wonson, Burkholder, Adam B., Perera, Lalith, Mack, Jasmine A., Miller, Frederick W., Fessler, Michael B., Cook, Donald N., Karmaus, Peer W. F., Nakano, Hideki, Garantziotis, Stavros, Madenspacher, Jennifer H., House, John S., Akhtari, Farida S., Schmitt, Charles S., Fargo, David C., Hall, Janet E., Motsinger-Reif, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321602/
https://www.ncbi.nlm.nih.gov/pubmed/37415598
http://dx.doi.org/10.3389/fgene.2023.1173676

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