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Lipoxin receptor agonist and inhibition of LTA(4) hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells
Airway diseases can disrupt tight junction proteins, compromising the epithelial barrier and making it more permeable to pathogens. In people with pulmonary disease who are prone to infection with Pseudomonas aeruginosa, pro-inflammatory leukotrienes are increased and anti-inflammatory lipoxins are...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321624/ https://www.ncbi.nlm.nih.gov/pubmed/37406028 http://dx.doi.org/10.1371/journal.pone.0287183 |