Hypoxia sensing requires H(2)S-dependent persulfidation of olfactory receptor 78

Oxygen (O(2)) sensing by the carotid body is critical for maintaining cardiorespiratory homeostasis during hypoxia. Hydrogen sulfide (H(2)S) signaling is implicated in carotid body activation by low O(2). Here, we show that persulfidation of olfactory receptor 78 (Olfr78) by H(2)S is an integral com...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Ying-Jie, Nanduri, Jayasri, Wang, Ning, Kumar, Ganesh K., Bindokas, Vytautas, Paul, Bindu D., Chen, Xuanmao, Fox, Aaron P., Vignane, Thibaut, Filipovic, Milos R., Prabhakar, Nanduri R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321732/
https://www.ncbi.nlm.nih.gov/pubmed/37406126
http://dx.doi.org/10.1126/sciadv.adf3026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321732/
https://www.ncbi.nlm.nih.gov/pubmed/37406126
http://dx.doi.org/10.1126/sciadv.adf3026

Ejemplares similares