Melanoma-intrinsic NR2F6 activity regulates antitumor immunity

Nuclear receptors (NRs) are implicated in the regulation of tumors and immune cells. We identify a tumor-intrinsic function of the orphan NR, NR2F6, regulating antitumor immunity. NR2F6 was selected from 48 candidate NRs based on an expression pattern in melanoma patient specimens (i.e., IFN-γ signa...

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Detalles Bibliográficos
Autores principales: Kim, Hyungsoo, Feng, Yongmei, Murad, Rabi, Pozniak, Joanna, Pelz, Carl, Chen, Yeqing, Dalal, Bhavik, Sears, Rosalie, Sergienko, Eduard, Jackson, Michael, Ruppin, Eytan, Herlyn, Meenhard, Harris, Curtis, Marine, Jean-Christophe, Klepsch, Victoria, Baier, Gottfried, Ronai, Ze’ev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10321753/
https://www.ncbi.nlm.nih.gov/pubmed/37406115
http://dx.doi.org/10.1126/sciadv.adf6621

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