Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning

Sugar porters (SPs) represent the largest group of secondary-active transporters. Some members, such as the glucose transporters (GLUTs), are well known for their role in maintaining blood glucose homeostasis in mammals, with their expression upregulated in many types of cancers. Because only a few...

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Detalles Bibliográficos
Autores principales: Mitrovic, Darko, McComas, Sarah E, Alleva, Claudia, Bonaccorsi, Marta, Drew, David, Delemotte, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322152/
https://www.ncbi.nlm.nih.gov/pubmed/37405846
http://dx.doi.org/10.7554/eLife.84805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322152/
https://www.ncbi.nlm.nih.gov/pubmed/37405846
http://dx.doi.org/10.7554/eLife.84805

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