Mechanism of fibroblast growth factor 21 in cardiac remodeling

Cardiac remodeling is a basic pathological process that enables the progression of multiple cardiac diseases to heart failure. Fibroblast growth factor 21 is considered a regulator in maintaining energy homeostasis and shows a positive role in preventing damage caused by cardiac diseases. This revie...

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Detalles Bibliográficos
Autores principales: Zhao, Zeyu, Cui, Xuemei, Liao, Zhangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322220/
https://www.ncbi.nlm.nih.gov/pubmed/37416922
http://dx.doi.org/10.3389/fcvm.2023.1202730
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author Zhao, Zeyu
Cui, Xuemei
Liao, Zhangping
author_facet Zhao, Zeyu
Cui, Xuemei
Liao, Zhangping
author_sort Zhao, Zeyu
collection PubMed
description Cardiac remodeling is a basic pathological process that enables the progression of multiple cardiac diseases to heart failure. Fibroblast growth factor 21 is considered a regulator in maintaining energy homeostasis and shows a positive role in preventing damage caused by cardiac diseases. This review mainly summarizes the effects and related mechanisms of fibroblast growth factor 21 on pathological processes associated with cardiac remodeling, based on a variety of cells of myocardial tissue. The possibility of Fibroblast growth factor 21 as a promising treatment for the cardiac remodeling process will also be discussed.
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spelling pubmed-103222202023-07-06 Mechanism of fibroblast growth factor 21 in cardiac remodeling Zhao, Zeyu Cui, Xuemei Liao, Zhangping Front Cardiovasc Med Cardiovascular Medicine Cardiac remodeling is a basic pathological process that enables the progression of multiple cardiac diseases to heart failure. Fibroblast growth factor 21 is considered a regulator in maintaining energy homeostasis and shows a positive role in preventing damage caused by cardiac diseases. This review mainly summarizes the effects and related mechanisms of fibroblast growth factor 21 on pathological processes associated with cardiac remodeling, based on a variety of cells of myocardial tissue. The possibility of Fibroblast growth factor 21 as a promising treatment for the cardiac remodeling process will also be discussed. Frontiers Media S.A. 2023-06-21 /pmc/articles/PMC10322220/ /pubmed/37416922 http://dx.doi.org/10.3389/fcvm.2023.1202730 Text en © 2023 Zhao, Cui and Liao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Zhao, Zeyu
Cui, Xuemei
Liao, Zhangping
Mechanism of fibroblast growth factor 21 in cardiac remodeling
title Mechanism of fibroblast growth factor 21 in cardiac remodeling
title_full Mechanism of fibroblast growth factor 21 in cardiac remodeling
title_fullStr Mechanism of fibroblast growth factor 21 in cardiac remodeling
title_full_unstemmed Mechanism of fibroblast growth factor 21 in cardiac remodeling
title_short Mechanism of fibroblast growth factor 21 in cardiac remodeling
title_sort mechanism of fibroblast growth factor 21 in cardiac remodeling
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322220/
https://www.ncbi.nlm.nih.gov/pubmed/37416922
http://dx.doi.org/10.3389/fcvm.2023.1202730
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